muscle. Multiple sequence and structure alignment with top benchmark scores scalable to thousands of sequences. Generates replicate alignments, enabling assessment of downstream analyses such as trees and predicted structures.
285usearch12. Open-source usearch
142reseek. Protein structure alignment and search algorithm
84urmap. URMAP ultra-fast read mapper
38palmscan. C++
27usearch_old_binaries. Executable files for usearch versions 5 through 11, donated to the public domain
24newick. Manipulate and generate figures for trees in Newick format
22palmdb. Database of virus RdRP barcode sequences
16palm_annot. Scripts, HMMs and search databases for identifying and classifying viral RdRp sequences
14viratax. Taxonomy classification of viral sequences / contigs
12syncmer. Validation of sycnmers compared to minimizers
11spades_circular_contigs. Python script to identify circular contigs from SPAdes assembler.
7palmscan2. C++
5rdrp_tree_experiments. Code, data and results for Muscle5 ensemble experiments on RdRp genus and phylum trees
5taxxi. Taxonomy cross-validating by identity
4re_coding_style. Robert C. Edgar's C++ coding style
4renomad. Implementation of NOMAD (https://doi.org/10.1101/2022.06.24.497555)
4pylddt. Python script to calculate LDDT and DALI Z score from MSA plus structures
3circuclust. Clustering and alignment for circular sequences
3jupiter. Generate "Jupiter" plots for circular genomes
2scop40c. Python
2usearch12_documentation. Documentation for USEARCH v12
2null_model2. Python
1tara_oceans. Data and scripts to reproduce my analysis of Tara Oceans data
1qscore. Compares a multiple alignment with a reference and reports accuracy scores.
1retree. Python Newick tree format parser and Robinson-Foulds calculator (self-teaching exercise)
1balifam. Protein multiple sequence alignment benchmark
1simple_paired_read_simulator. A simple paired-read simulator in stand-alone Python2
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