Bioinformatics at the intersection of systems biology, machine learning, and functional genomics.
gia. gia: Genomic Interval Arithmetic
67bedrs. bedtools-like functionality for interval sets in rust
55paraseq. A minimal copy fastq and fasta reader built for parallel support and paired end processing
45ggetrs. Efficient querying of biological databases
44adpbulk. pseudobulking on an AnnData object
37ibu. a rust library for high throughput binary encoding of genomic sequences
11sgcount. A flexible and fast sgRNA counter from FASTQ Files
11crispr_screen. Efficient Differential Expression and Gene Aggregation for CRISPR screens.
10bitnuc. A library for efficient nucleotide sequence manipulation using 2-bit encoding
10geomux. hypergeometric testing of guide RNA identity to assign cell barcodes to a guide identity
7seq_io_parallel. a map-reduce parallel processing extension for seq_io
6idea. Integrated Differential Expression and Annotation
6nucgen. A fast and simple configurable fast[aq] generator
6seqpls. "My sequences please" - a paired fastq grepper
5graph-canon. Generate canonical labels for graphs built on NAUTY
5qgpu. A simple job scheduler across multi-node gpus
5pipspeak. a CLI tool to whitelist filter pipseq reads and convert them to a 10X-style format
5screenviz. crispr screen visualization toolkit
5memoesu. subgraph enumeration on graphs using a memoized parallel ESU algorithm
4splici. a rust implementation of the splici algorithm to build spliced/unspliced transcripts
4yaflux. A lightweight, declarative framework for Python analysis workflows.
3gtftools. a parser for gtf built using nom
3cshift. A tool to perform cluster enrichment/depletion analyses
3alpha-rra. an implementation of αRRA for aggregating grouped p-values
2graph6-rs. a rust library for graph6 formatted files from NAUTY
2fxtools. a collection of CLI utilities for processing fasta/fastq (FASTX) files.
2dgcount. Dual guide CRISPR counting
2casmap. Mapping sgRNA counts for cas12 6-mer CRISPR screens
2graphtries. a rust implementation of the gtries subgraph enumeration algorithm
1dirio. a simple CLI to track and report disk usage over some subcommand runtime
1pvsvg. a python wrapper of the vis.js network visualization library with an additional ability to export static SVG
1information. ndarray-based information theory utilities
1bitnuc-mismatch. Create unambiguous one-off mismatch hash tables from bitnuc scalars
1art_or_trash. is it art? or is it trash?
1gtfjson. A simple CLI utility to convert a GTF file to NDJSON for fast parsing
1muxsim. a python module for generate cell / guide matrices for demultiplex testing
1ClusterDock. Pipeline and analysis scripts for k-mean based clustering of DOCK
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