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datascience. Curated list of Python resources for data science.
★ 4.6klinuxhelp. Helpful linux commands.
★ 203sashelp. SAS code snippets
★ 39ml_checklist. Explorative Data Analysis Guidelines
★ 23adventofcode2020. Python solutions to https://adventofcode.com/2020
★ 16adventofcode2022. Advent of Code 2022
★ 5adventofcode2021. Advent of Code 2021
★ 3latexhelp. Latex code snippets
★ 2sample_datasets.
★ 2adventofcode2019. Advent of Code 2019
★ 1adventofcode2018. Advent of Code 2018
★ 1adventofcode2025. Advent of Code 2025
★ 1quickdraw-dataset. Documentation on how to access and use the Quick, Draw! Dataset.
★ 6.8kopenobserve. Open source observability platform for logs, metrics, traces, frontend monitoring, pipelines and LLM observability. A sophisticated, simple and highly performant alternative to Datadog, Splunk, and Elasticsearch with 140x lower storage costs and single binary deployment.
★ 20kandrej-karpathy-skills. A single CLAUDE.md file to improve Claude Code behavior, derived from Andrej Karpathy's observations on LLM coding pitfalls.
★ 198kFiraCode. Free monospaced font with programming ligatures
★ 82kget-shit-done. A light-weight and powerful meta-prompting, context engineering and spec-driven development system for Claude Code by TÂCHES.
★ 65kggannotate. Interactively annotate ggplots
★ 401tidytuesday. Code and plots for submissions to the #tidytuesday challenge
★ 789stat_rethinking_2026. Statistical Rethinking Course 2026
★ 813pandas-ai. Chat with your database or your datalake (SQL, CSV, parquet). PandasAI makes data analysis conversational using LLMs and RAG.
★ 24k2025-advent-of-code. https://adventofcode.com/2025
★ 2grist-core. Grist is the evolution of spreadsheets.
★ 11kplotly-resampler. Visualize large time series data with plotly.py
★ 1.2kvisidata. A terminal spreadsheet multitool for discovering and arranging data
★ 9.2kharlequin. The SQL IDE for Your Terminal.
★ 6.3klejepa. Python
★ 1.3kdatamapplot. Creating beautiful plots of data maps
★ 1kdeepdiff. DeepDiff: Deep Difference and search of any Python object/data. DeepHash: Hash of any object based on its contents. Delta: Use deltas to reconstruct objects by adding deltas together.
★ 2.5kmetabase. The easy-to-use open source Business Intelligence and Embedded Analytics tool that lets everyone work with data :bar_chart:
★ 48kDABEST-python. Data Analysis with Bootstrapped ESTimation
★ 379mise. dev tools, env vars, task runner
★ 31klabelU. Open-source multimodal data annotation platform with AI auto-annotation support.
★ 1.6kflet. Build realtime web, mobile and desktop apps in Python only. No frontend experience required.
★ 16kkivy. Open source UI framework written in Python, running on Windows, Linux, macOS, Android and iOS
★ 19kdoccano. Open source annotation tool for machine learning practitioners.
★ 11kact. Run your GitHub Actions locally 🚀
★ 71ksample-databricks-python. An educational data engineering project template that uses Databricks as a computation engine that allows to combine engineering best practices with notebook-centric layout
★ 5release-please. generate release PRs based on the conventionalcommits.org spec
★ 7.3kcoder. Secure environments for developers and their agents
★ 14kyt-dlp. A feature-rich command-line audio/video downloader
★ 181kquarto-cli. Open-source scientific and technical publishing system built on Pandoc.
★ 5.9kdeepface. A Lightweight Face Recognition and Facial Attribute Analysis (Age, Gender, Emotion and Race) Library for Python
★ 23kGaga. [TMLR 2026] Gaga: Group Any Gaussians via 3D-aware Memory Bank
★ 413LAVIS. LAVIS - A One-stop Library for Language-Vision Intelligence
★ 11kkotaemon. An open-source RAG-based tool for chatting with your documents.
★ 26kmarkitdown. Python tool for converting files and office documents to Markdown.
★ 170kinfluxdb. Scalable datastore for metrics, events, and real-time analytics
★ 32ksamurai. Official repository of "SAMURAI: Adapting Segment Anything Model for Zero-Shot Visual Tracking with Motion-Aware Memory"
★ 7.1kdifflogic. A Library for Differentiable Logic Gate Networks
★ 796fd. A simple, fast and user-friendly alternative to 'find'
★ 44khyperfine. A command-line benchmarking tool
★ 29kGaussianAnything. High-quality and editable surfel 3D Gaussian generation through native 3D diffusion (ICLR 2025)
★ 408data-engineer-handbook. This is a repo with links to everything you'd ever want to learn about data engineering
★ 43kBeatTheBookie. Betting Strategy to Beat the Bookies at Football Games
★ 651AFFiNE. There can be more than Notion and Miro. AFFiNE(pronounced [ə‘fain]) is a next-gen knowledge base that brings planning, sorting and creating all together. Privacy first, open-source, customizable and ready to use.
★ 71kstreamlit-highcharts-python. Streamlit Component providing Highcharts Core for Python support
★ 4highcharts-core. Python wrapper for the Highcharts Core JavaScript library
★ 71pyparsing. Python library for creating PEG parsers
★ 2.5kbrush. 3D Reconstruction for all
★ 4.9kstealth. :rocket: Stealth - Secure, Peer-to-Peer, Private and Automateable Web Browser/Scraper/Proxy
★ 1.1ksudoku-in-python-packaging. Sudoku solving in python packaging
★ 451supabase. The Postgres development platform. Supabase gives you a dedicated Postgres database to build your web, mobile, and AI applications.
★ 107kSegmentAnything3D. [ICCV'23 Workshop] SAM3D: Segment Anything in 3D Scenes
★ 1.4kgit-remote-s3. Python
★ 792trufflehog. Find, verify, and analyze leaked credentials
★ 27kgitleaks. Find secrets with Gitleaks 🔑
★ 28klucia. Authentication, simple and clean
★ 10kcopenhagen. A basic guideline on implementing auth for the web
★ 2.1kml-depth-pro. Depth Pro: Sharp Monocular Metric Depth in Less Than a Second.
★ 5.6kPotreeConverter. Create multi res point cloud to use with potree
★ 813uptime-kuma. A fancy self-hosted monitoring tool
★ 90klibLAS. C++ library and programs for reading and writing ASPRS LAS format with LiDAR data
★ 332LAStools. efficient tools for LiDAR processing
★ 1.1kpotree. WebGL point cloud viewer for large datasets
★ 5.6kawesome-pipeline. A curated list of awesome pipeline toolkits inspired by Awesome Sysadmin
★ 6.6kvisual_anagrams. Code for the paper "Visual Anagrams: Generating Multi-View Optical Illusions with Diffusion Models"
★ 968ISBNet. ISBNet: a 3D Point Cloud Instance Segmentation Network with Instance-aware Sampling and Box-aware Dynamic Convolution (CVPR 2023)
★ 167GrowSP. 🔥GrowSP in PyTorch (CVPR 2023)
★ 2013DPC-CISS. This is the code related to "Geometry and Uncertainty-Aware 3D Point Cloud Class-Incremental Semantic Segmentation" (CVPR 2023)
★ 41pooch. A friend to fetch your data files
★ 733Open3D. Open3D: A Modern Library for 3D Data Processing
★ 14kstructlog. Simple, powerful, and fast logging for Python.
★ 4.9kray. Ray is an AI compute engine. Ray consists of a core distributed runtime and a set of AI Libraries for accelerating ML workloads.
★ 43kprometheus. The Prometheus monitoring system and time series database.
★ 65kgitops-template. ArgoCD based GitOps template with preconfigured Glasskube Package Manager and an example application.
★ 181CloudCompare. CloudCompare main repository
★ 4.6kClickHouse. ClickHouse® is a real-time analytics database management system
★ 49kpykan. Kolmogorov Arnold Networks
★ 16kCrossSection. Code to accompany our paper Chen and Zimmermann (2020), "Open source cross-sectional asset pricing"
★ 1kmagic-wormhole. get things from one computer to another, safely
★ 23kcroc. Easily and securely send things from one computer to another :crocodile: :package:
★ 39ksherloq. An open-source digital image forensic toolset
★ 3.2kCausalCookbook.
★ 22jailbreak_llms. [CCS'24] A dataset consists of 15,140 ChatGPT prompts from Reddit, Discord, websites, and open-source datasets (including 1,405 jailbreak prompts).
★ 3.8kmarginaleffects. R package to compute and plot predictions, slopes, marginal means, and comparisons (contrasts, risk ratios, odds, etc.) for over 100 classes of statistical and ML models. Conduct linear and non-linear hypothesis tests, or equivalence tests. Calculate uncertainty estimates using the delta method, bootstrapping, or simulation-based inference
★ 629awesome-mlops. :sunglasses: A curated list of awesome MLOps tools
★ 5.2klangkit. 🔍 LangKit: An open-source toolkit for monitoring Large Language Models (LLMs). 📚 Extracts signals from prompts & responses, ensuring safety & security. 🛡️ Features include text quality, relevance metrics, & sentiment analysis. 📊 A comprehensive tool for LLM observability. 👀
★ 994sops. Simple and flexible tool for managing secrets
★ 23kkeycloak. Open Source Identity and Access Management For Modern Applications and Services
★ 36kHTSplotter. An end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screens
★ 5cellpose. a generalist algorithm for cellular segmentation with human-in-the-loop capabilities
★ 2.3kcyto-dl. Python
★ 32FriendsDontLetFriends. Friends don't let friends make certain types of data visualization - What are they and why are they bad.
★ 7.1kxg2xg. by ex-googlers, for ex-googlers - a lookup table of similar tech & services
★ 16kzoekt. Fast trigram based code search
★ 1.8kdspguide-code. Python and Octave/MATLAB explorations of algorithms from The Scientist and Engineer's Guide to Digital Signal Processing
★ 36pyvips. python binding for libvips using cffi
★ 813IMCWorkflow. Overview repository on IMC data analysis
★ 9steinbock. A toolkit for processing multiplexed tissue images
★ 69kargo. Application lifecycle orchestration
★ 3.4kopenapi-generator. OpenAPI Generator allows generation of API client libraries (SDK generation), server stubs, documentation and configuration automatically given an OpenAPI Spec (v2, v3)
★ 27kargo-cd. Declarative Continuous Deployment for Kubernetes
★ 24kFizzBuzzEnterpriseEdition. FizzBuzz Enterprise Edition is a no-nonsense implementation of FizzBuzz made by serious businessmen for serious business purposes.
★ 24kawesome-argo. A curated list of awesome projects and resources related to Argo (a CNCF graduated project)
★ 2.5kfabric. Simple, Pythonic remote execution and deployment.
★ 15kearthly. Super simple build framework with fast, repeatable builds and an instantly familiar syntax – like Dockerfile and Makefile had a baby.
★ 12kpromptfoo. Test your prompts, agents, and RAGs. Red teaming/pentesting/vulnerability scanning for AI. Compare performance of GPT, Claude, Gemini, DeepSeek, and more. Simple declarative configs with command line and CI/CD integration. Used by OpenAI and Anthropic.
★ 24kcellprofiler-batch-nf. Batch execution of CellProfiler analyses using Nextflow
★ 4FastSAM. Fast Segment Anything
★ 8.4kMetricsReloaded. Python
★ 102micro-sam. Segment Anything for Microscopy
★ 706ibis. the portable Python dataframe library
★ 6.6kawesome-causal-inference. A curated list of causal inference libraries, resources, and applications.
★ 1.2kno-more-secrets. A command line tool that recreates the famous data decryption effect seen in the 1992 movie Sneakers.
★ 7.8kgithub-spray. :octocat: Draw on your GitHub contribution graph ░▒▓█
★ 1.5ktry. Control and manipulate a command's effects before modifying your live system
★ 5.5kDragGAN. Official Code for DragGAN (SIGGRAPH 2023)
★ 36kprogress. Linux tool to show progress for cp, mv, dd, ... (formerly known as cv)
★ 8.9kvizarr. A minimal Zarr image viewer based on Viv.
★ 198neural-tangents. Fast and Easy Infinite Neural Networks in Python
★ 2.4kMEDIAR. (NeurIPS 2022 CellSeg Challenge - 1st Winner) Open source code for "MEDIAR: Harmony of Data-Centric and Model-Centric for Multi-Modality Microscopy"
★ 158PlateEditor. Repository for PlateEditor, the web application allowing management of plate layout, results visualization and analysis
★ 22segment-anything. The repository provides code for running inference with the SegmentAnything Model (SAM), links for downloading the trained model checkpoints, and example notebooks that show how to use the model.
★ 55kseg. Evaluation of label free cell and nuclei segmentation
★ 9cog. Containers for machine learning
★ 9.4kcylinter. An Interactive Image Segmentation Filter for Multiplex Microscopy
★ 35Oxen. Lightning fast data version control system for large repositories of data. Feels like git, pushes and pulls like oxen.
★ 1.2kRath. Next generation of automated data exploratory analysis and visualization platform.
★ 4.7kinstruct-pix2pix. Python
★ 6.9kdance. DANCE: a deep learning library and benchmark platform for single-cell analysis
★ 389chatgpt-failures. Failure archive for ChatGPT and similar models
★ 595nnUNet. Python
★ 8.7kmarp. The entrance repository of Markdown presentation ecosystem
★ 12kWIPP. Web Image Processing Pipeline (WIPP)
★ 27dynamicviz. Jupyter Notebook
★ 64AdventOfCode2022. Python
★ 2commitgpt. Automatically generate commit messages using ChatGPT
★ 1.6kAdvent-of-Code. Python
★ 1aoc_2022. Python
★ 2Aoc22. Advent of Code 2022
★ 1WBC_Feature. Classification of White Blood Cells in Peripheral Smear Images
★ 18mark. Sync your markdown files with Confluence pages.
★ 1.5ktorchinfo. View model summaries in PyTorch!
★ 2.9kawesome-open-mlops. The Fuzzy Labs guide to the universe of open source MLOps
★ 482scPerturb. scPerturb: A resource and a python/R tool for single-cell perturbation data
★ 183single-cell-tutorial. Single cell current best practices tutorial case study for the paper:Luecken and Theis, "Current best practices in single-cell RNA-seq analysis: a tutorial"
★ 1.6kengineeringladders. A framework for Engineering Managers
★ 8.5kInterviewThis. An open source list of developer questions to ask prospective employers
★ 6.9kstable-diffusion. A latent text-to-image diffusion model
★ 73kCLAM. Open source tools for computational pathology - Nature BME
★ 1.7kPORPOISE. Pan-Cancer Integrative Histology-Genomic Analysis via Multimodal Deep Learning - Cancer Cell
★ 248diffusers. 🤗 Diffusers: State-of-the-art diffusion models for image, video, and audio generation in PyTorch.
★ 34kNAFNet. The state-of-the-art image restoration model without nonlinear activation functions.
★ 3.1kcellpainting-gallery. Cell Painting Gallery
★ 136linearsdr. Linear Sufficient Dimension Reduction methods
★ 3comcast. Simulating shitty network connections so you can build better systems.
★ 11kstable-diffusion. Jupyter Notebook
★ 1knapari. napari: a fast, interactive, multi-dimensional image viewer for python
★ 2.7kGeneMutationFromHE. Gene mutation and pathway activity prediction from H&E slides
★ 37HRDA. [ECCV22] Official Implementation of HRDA: Context-Aware High-Resolution Domain-Adaptive Semantic Segmentation
★ 267Supp_BetgeRindtorff_2021. Repository for the paper "The drug-induced phenotypic landscape of colorectal cancer organoids"
★ 8cellx-predict. Explainable AI model of cell behavior
★ 20discoart. 🪩 Create Disco Diffusion artworks in one line
★ 3.8kprettymaps. Draw pretty maps from OpenStreetMap data! Built with osmnx +matplotlib + shapely
★ 12keeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee. eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee
★ 11kprintf-tac-toe. tic-tac-toe in a single call to printf
★ 2.5ktilt. Define your dev environment as code. For microservice apps on Kubernetes.
★ 10kfeathr. Feathr – A scalable, unified data and AI engineering platform for enterprise
★ 1.9kdeep-spectral-segmentation. [CVPR 2022] Deep Spectral Methods: A Surprisingly Strong Baseline for Unsupervised Semantic Segmentation and Localization
★ 240campa. Conditional Autoencoders for Multiplexed Pixel Analysis
★ 19perceiver-io. A PyTorch implementation of Perceiver, Perceiver IO and Perceiver AR with PyTorch Lightning scripts for distributed training
★ 535font-thicccboi. A free and open source font by Wonder Unit
★ 187memray. Memray is a memory profiler for Python
★ 15kAwesome-Diffusion-Models. A collection of resources and papers on Diffusion Models
★ 12klatent-diffusion. High-Resolution Image Synthesis with Latent Diffusion Models
★ 14kSIMPLI. SIMPLI is a highly configurable pipeline for the analysis of multiplexed imaging data.
★ 38slim. Slim(toolkit): Don't change anything in your container image and minify it by up to 30x (and for compiled languages even more) making it secure too! (free and open source)
★ 23kprefetch_generator. Simple package that makes your generator work in background thread
★ 283rethinking. Statistical Rethinking course and book package
★ 2.4kchemicalx. A PyTorch and TorchDrug based deep learning library for drug pair scoring. (KDD 2022)
★ 783causal-inference-visual-guides. A collection of visual guides to help applied scientists learn causal inference.
★ 305python-causality-handbook. Causal Inference for the Brave and True. A light-hearted yet rigorous approach to learning about impact estimation and causality.
★ 3.4kcausalml-feedstock. A conda-smithy repository for causalml.
★ 4redun. Yet another redundant workflow engine
★ 596cosmic-ray. Mutation testing for Python
★ 646mutmut. Mutation testing system
★ 1.4kvicreg. VICReg official code base
★ 577EASI-FISH. Tools and scripts for EASI-FISH image data analysis
★ 17cats. CATS is a REST API Fuzzer and negative testing tool for OpenAPI endpoints. CATS automatically generates, runs and reports tests with minimum configuration and no coding effort. Tests are self-healing and do not require maintenance.
★ 1.4kstat_rethinking_2022. Statistical Rethinking course winter 2022
★ 4.1kKaggle-Recursion-Cellular. https://www.kaggle.com/c/recursion-cellular-image-classification
★ 40ConvNeXt. Code release for ConvNeXt model
★ 6.4kmae. PyTorch implementation of MAE https//arxiv.org/abs/2111.06377
★ 8.4kdura. You shouldn't ever lose your work if you're using Git
★ 4.4kAdvent-of-Code. Advent of Code
★ 12aoc21. Python
★ 1Awesome-Visual-Transformer. Collect some papers about transformer with vision. Awesome Transformer with Computer Vision (CV)
★ 3.6kSegFormer. Official PyTorch implementation of SegFormer
★ 3.6kSwin-Transformer. This is an official implementation for "Swin Transformer: Hierarchical Vision Transformer using Shifted Windows".
★ 16krational_activations. Rational Activation Functions - Replacing Padé Activation Units
★ 107python_for_microscopists. https://www.youtube.com/channel/UC34rW-HtPJulxr5wp2Xa04w?sub_confirmation=1
★ 4.4k